Are assisted reproductive technology (ART) treatment factors or infertility diagnoses associated with autism among ART-conceived children?
Our study suggests that the incidence of autism diagnosis in ART-conceived children during the first 5 years of life was higher when intracytoplasmic sperm injection (ICSI) was used compared with conventional IVF, and lower when parents had unexplained infertility (among singletons) or tubal factor infertility (among multiples) compared with other types of infertility.
Kissin, D.M., Y. Zhang, S.L. Boulet, C. Fountain, P. Bearman, L. Schieve, M. Yeargin-Allsopp and D.J. Jamieson. 2014. "Association of assisted reproductive technology (ART) treatment and parental infertility diagnosis with autism in ART-conceived children," Human Reproduction; doi: 10.1093/humrep/deu338.